Hunter S Thompson – Fear and Loathing in Las Vegas: Savage Journey to Heart of American Dream + genaro – Killing the Myth + Merck | Sigma Aldrich – Adrenochrome

Fear and Loathing in Las Vegas: A Savage Journey to the Heart of the American Dream

Fear and Loathing in Las Vegas: A Savage Journey to the Heart of the American Dream

Fear and Loathing in Las Vegas: A Savage Journey to the Heart of the American Dream
Hunter S Thompson
Knopf Doubleday Publishing Group
29 september 2010
224 pagina’s

This cult classic of gonzo new journalism is the best chronicle of drug soaked, addle brained, rollicking good times ever committed to the printed page. It is also the tale of a long weekend road trip that has gone down in the annals of American pop culture as one of the strangest journeys ever undertaken.

Now a major motion picture from Universal, directed by Terry Gilliam and starring Johnny Depp and Benicio del Toro.

Killing the Myth: Adrenochrome

White Rabbit (foto Merck)

genaro. “Killing the Myth: An Experience with Adrenochrome (exp51847)”, March 28, 2006.

DOSE 100 miligram sublingual Adrenochrome (freebase)
BODY WEIGHT 67 kilogram

Compound used
D,L Adrenochrome freebase (synthetic, 99,98% purity)
CAS [56 06 8]

Adrenochrome (freebase)
3 Hydroxy 1 Methyl 5,6 Indolinedione, 2,3 Dihydro
3 Hydroxy 1 Methyl 1H Indole 5,6 Dione

D, L means it is a racemate, which means it is an Equimolar mixture of two of enantiomers: the D Adrenochrome and the L Adrenochrome (also called (-) Adrenochrome et (+) Adrenochrome respectively)

Adrenochrome has been described as a hallucinogen or psychotomimetic and a cholinesterase inhibitor. It has also Haemostatic properties (meaning that it is something that stops bleeding).

Description of the powder a close up of the Adrenochrome crystals shows a dark red color but the powder seems just like dried blood to the naked eye, meaning some slightly orangy brown color. But if I dissolve some crystals into a few drops of water I will get a blood red to bright red solution (depending on the concentration), exactly the same color as Mercurochrome. It has a slightly metallic chemical taste which somewhat reminded me of the taste of blood but it was much more tasteless (less bitter).

Most labs sell D, L Adrenochrome (CAS 56 06 8) at 70 to 100 euros for 250 miligram. But I recently found another chemical supplier selling a product named ‘Adrenochrome‘ at 110 euros for 50 gram, the price difference is so huge that I first though it couldn’t be the same compound that other suppliers were selling, but CAS number was 56 06 8 so it was deffinately the same Adrenochrome. Such a price difference seems strange to me, I thought maybe it could be one of the two enantiomers (instead of the D, L form) but this wouldn’t be logical as separating two enantiomers is complicated and therefore one enantiomer alone should be more expensive than the D, L form, and certainly not cheaper.

Adrenochrome is quickly oxidised and should be kept away from air, light, humidity and heat. Therefore it is kept in an airtight container which is put in the freezer. Even this way, it will slowly decompose so it should not be kept for too long before use.

My experimentations with Adrenochrome

I had acquired D, L Adrenochrome freebase (the one sold at 70 euros for 250 miligram)

First trial: I held 100 mg under my tongue for one minute and then swallowed. Fast onset (about five minutes)

Second trial I snorted 50 mg Onset a few seconds.

Third trial I smoked 25 mg (vaporised in a crack pipe). Onset is almost instant.

Note that I waited a few days between each trial.

The three trials gave me the exact same effects, which were very light and really uninteresting. I wouldn’t even call it a high.

First, it’s wasn’t hallucinogen nor psychedelic. I had a feeling of warmth through my body, I felt a numbness in my hands and my head (possibly linked to the Haemostatic effect), there was some slight sedation, and a very slight short lived euphoria (the euphoria was a slightly more pronounced when smoked, but still very short lived)
There’s also some minor visual change (no visuals, just that I would see the room slightly differently than usual, but honestly that was some really minor change, a joint of hashish would have done the same, nothing really noticeable). There might be some slight myosis too (= little pupils), not really sure.

To sum up, effects were extremely weak, absolutely not fun nor psychedelic in anyway, and short lived (I would say the slight initial euphoria is gone within four five minutes, and the few strange feelings that I experience from the stuff are gone within about one hour (I couldn’t say the exact duration as I didn’t really checked my watch)
Needless to say I was very disappointed by this uninteresting compound.

The effects I had from it were flimsy, there was a definite effect on my vision and my mental state for sure but I would definitely not call it ‘hallucinogenic‘.

So, I might have wanted to try higher dosages just in case this could intensify any effects (let’s say 250 miligram orally, 100 mg snorted and 100 mg vaporised), or I might have wanted to try the other Adrenochrome (the one sold at 110 euro 50 gram) just to make sure it is the same. But I didn’t as I had better things to do with my money and I was pretty sure that even if this would give me some more effect, that would still be of poor recreational and spiritual interest.

Also, about possible secondary effects of Adrenochrome: as it is an Haemostatic compound (prevents capillary bleeding during injury) it is not impossible that excessive use would end up causing blood circulation troubles, furthermore some scientists seem to say that Adrenochrome is known to cause Cardio Vascular troubles.

To conclude I would say that this is an uninteresting substance to my opinion, and furthermore it’s possibly a dangerous one.

Expiration Year 2004
Expiration ID 51847
Gender Male
Age at time of experience Not Given
Published March 28, 2006


C9H9NO3 (foto Sigma Aldrich)

Synonym 3 Hydroxy 1 Methyl 5,6 Indolinedione
CAS Number 54 06 8
Empirical Formula (Hill Notation) C9H9NO3
Molecular Weight 179.17
EC Number 200 192 8
MDL number MFCD00069732
PubChem Substance ID 24891016


Certificate of Analysis (COA)
Specification Sheet

SKU Pack Size Availability Pack Size Price (EUR) Quantity

A5752 25 MG Only 6 left in stock (more on the way) FROM 104.00

A5752 250 MG Only 2 left in stock (more on the way) FROM 250 mg 557.00

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